Research Article
Antibiotic Consumption and Bacterial Resistance Pattern During Three Years at a Tertiary Hospital in Mashhad, Eastern Iran
Sepideh Hasanzadeh,
Ali Mehri,
Mahin Sadat Shahabifar,
Kiarash Ghazvini*
Issue:
Volume 9, Issue 4, December 2023
Pages:
95-99
Received:
Jan. 05, 2023
Accepted:
Aug. 01, 2023
Published:
Nov. 24, 2023
DOI:
10.11648/j.jher.20230904.11
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Abstract: One of the most significant global public health challenges is antimicrobial resistance (AMR). Improper use of antibiotics is among the leading causes of drug resistance to various substances. In Eastern Iran's Mashhad, a tertiary hospital has undertaken research on antibiotic usage and bacterial resistance patterns for three years, as part of a regional action plan to combat healthcare-associated illnesses. The Ghaem hospital's pharmacy and microbiology lab have diligently collected information on antibiotic use and bacterial resistance over this period. The data revealed that Meropenem, Ceftriaxone, and Ciprofloxacin were the most frequently used antibiotics in 2017, 2018, and 2019, respectively. Between 2017 and 2019, E. coli, A. baumannii, and K. pneumonia exhibited significant changes in their resistance rates (RR) to various antibiotic classes, with the exception of Imipenem. Notably, S. aureus displayed declining trends in Ciprofloxacin RRs. Our findings indicate a reduction in the use of several antibiotics at Ghaem hospital during this period, while Metronidazole, Imipenem, and Cefepime remained preferred choices. The overuse of broad-spectrum antimicrobials has resulted in serious public health issues. Hence, continued efforts are essential to optimize antibiotic administration, mitigate antibiotic resistance, and gather additional data for policy-making.
Abstract: One of the most significant global public health challenges is antimicrobial resistance (AMR). Improper use of antibiotics is among the leading causes of drug resistance to various substances. In Eastern Iran's Mashhad, a tertiary hospital has undertaken research on antibiotic usage and bacterial resistance patterns for three years, as part of a re...
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